Supporting heartworm resistance surveillance across Europe

In a recent European research project, scientists examined the genetic markers associated with heartworm (Dirofilaria immitis) resistance to macrocyclic lactone (ML) treatments—commonly used preventatives for heartworm disease. Using advanced droplet digital PCR, they analyzed genetic single nucleotide polymorphism (SNP) markers that may flag resistance to these widely used medications. Samples included two reference strains from the USA and 25 clinical samples of adult worms or microfilariae taken from domestic dogs across EuropePubMed.

Our team at PCG coordinated and facilitated the collection and shipment of clinical samples from Romania. Working with our network of veterinary practitioners and diagnostic labs across the country, we secured specimens that were essential to the study's genetic surveillance efforts. This involved identifying eligible samples, ensuring they were properly collected and preserved, and managing logistics to get them to the central testing lab.